Submandibular gland transfer for the prevention of postradiation xerostomia in patients with head and neck cancer: a systematic review and meta-analysis.
نویسندگان
چکیده
BACKGROUND Submandibular gland transfer has been widely used to prevent postradiation xerostomia in head-and-neck cancers. However, there are still some controversies. METHODS Six databases were searched, data extraction was performed and the risk of bias was assessed by 2 reviewers independently. The meta-analysis was performed using Review Manager, version 5.2. RESULTS A total of 7 trials (12 articles) and 369 participants were included. CONCLUSIONS The present clinical evidence suggests that submandibular gland transfer might be highly effective to prevent postradiation xerostomia in head-and-neck cancers without serious adverse events. However, more randomized controlled trials are still needed to confirm this conclusion.
منابع مشابه
Quantitative assessment of salivary gland function by radioisotopic scanning in a randomized trial of Pilocarpine for prevention of radiation induced Xerostomia [Persian]
Introduction: Radioisotope scanning is the best method for objective assessment of salivary gland function. Thus, it was used in a randomized trial of concomitant pilocarpine for assessment of radiation-induced xerostomia, in addition to subjective evaluation by an approved questionnaire and objective standard xerostomia grading. Methods: Patients randomized in placebo-controlled trial of...
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عنوان ژورنال:
- ORL; journal for oto-rhino-laryngology and its related specialties
دوره 77 2 شماره
صفحات -
تاریخ انتشار 2015